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CDC25B-IN-1 is a small-molecule inhibitor of the CDC25B phosphatase used for biochemical and cellular research. Reported as compound 4a, it inhibits CDC25B with a Ki of 8.5 μM, reduces cell proliferation and colony formation, and induces G2/M cell-cycle arrest. The material is typically supplied as a light brown oil or as a DMSO solution for assay use.
Inhibits CDC25B with a reported Ki of 8.5 μM.
Reduces cell proliferation and colony formation in cellular assays.
Induces G2/M cell-cycle arrest.
Molecular formula C20H19NO3; molecular weight 321.37.
High purity (approximately 98.1%; may vary by batch).
Available in multiple quantities and solution formats for assay convenience.
Storage recommendations include refrigeration under inert atmosphere and low-temperature storage in solvent.
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CAY 10465 is a selective and high-affinity AhR agonist with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). This compound reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibits the synthesis of the protein.
Selective and high-affinity AhR agonist
No effect on estrogen receptor
Reduces apolipoprotein A-I levels in HepG2 cells
Inhibits protein synthesis
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VU0467485 (AZ13713945) is a potent, selective, orally bioavailable positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor M4 supplied as a solid research reagent for preclinical studies.
Potent and selective M4 receptor positive allosteric modulator.
Orally bioavailable in preclinical models.
High purity solid suitable for research applications.
Provided in small milligram pack sizes for preclinical dosing.
Molecular formula C17H17FN4O2S; molecular weight 360.41 g/mol.
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CUDA is a research-grade small-molecule inhibitor of soluble epoxide hydrolase (sEH) used in biochemical and cellular studies to probe sEH and PPAR-alpha pathways. It is supplied as a crystalline solid (CAS 479413-68-8) with molecular formula C19H36N2O3 and molecular weight 340.50 g/mol.
Potent sEH inhibitor with IC50 = 11.1 nM (mouse) and 112 nM (human).
High purity by HPLC (approximately 99.8%).
Supplied in small solid quantities suitable for assay development and cellular studies.
Soluble in common organic solvents for stock solution preparation.
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Creatine (Standard) is an analytical standard of Creatine, an endogenous amino acid derivative crucial for cellular energy in muscle and brain. It is designed for research and analytical applications, serving as a reference in various assays.
Used in qualitative research experiments.
Used in quantitative research experiments.
Used in methodological research experiments.
Applicable in HPLC.
Applicable in GC.
Applicable in MS.
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